The transport and communications infrastructure in the DRN is rather diverse and good network. The region is connected to the European and Eastern-European markets via an international road route (Giurgiulesti-Briceni Corridor) and two national routes (M14 and M2). At the same time, the intra-regional road network provides high mobility from North to South and from East to West for labor mobility and the sale of agricultural products in urban centers. And the relatively high road density in relation to the population number (the highest in the regional profile) creates all the premises for the movement of goods and passenger traffic, which ultimately leads to the increase of the social and economic development indicators.

RDN is the only region that has the opportunity of air access through two airports – Balti International Airport and Marculesti International Free Airport.

The density of railway networks in the DRN is the smallest in the country and is of 2.1 km/, being below the national average of 3.3km/100 The main railway nodes in the region are the city of Balti and the town of Ocnita. Through these connections, the Moldovan rail routes diversify and include the following destinations: Russia (Moscow and St. Petersburg), Belarus (Minsk), Ukraine (Kiev, Chernivtsy, Ivano-Frankovsk, etc.).

There are two border crossing points on the territory of the Region, which are used at minimum capacity, both for freight transport and for passenger transport: the Soroca-Tekinovka ferry and the Cosauti-Yampol ferry.